| Left atrial speckle tracking analysis in patients with mitral insufficiency and history of paroxysmal atrial fibrillation. | |
| | |
MedLine Citation:
|
PMID: 22130899 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The occurrence of atrial fibrillation (AF), especially in patients with mitral regurgitation (MR), is related to the degree of left atrial (LA) myopathy, remodeling and fibrosis, that are responsible of LA electrical inhomogeneity and abnormal conduction velocities. Speckle tracking echocardiography (STE) has recently enabled the quantification of longitudinal myocardial LA deformation dynamics. Our aim was to investigate by STE the effects of the occurrence of paroxysmal AF on LA myocardial deformation, in a population of patients with asymptomatic chronic MR. We compared two groups of a total of 197 patients with MR: 54 with history of paroxysmal AF and 143 with MR alone. Subgroups were created according to MR degree. Peak atrial longitudinal strain (PALS) was measured in all subjects. Values were obtained by averaging all segments (global PALS), measured in the 4-chamber and 2-chamber views. Compared to the mild MR group (46.1 ± 4.9%), global PALS was lower in moderate MR group (22.1 ± 5.8%) and further reduced in the severe MR group (13.9 ± 4.2%; overall P < 0.0001 by ANOVA, P < 0.05 for all pair-wise comparisons). Besides, in each MR group, patients with history of paroxysmal AF presented a global PALS significantly reduced (overall P < 0.0001 by ANOVA). After multivariate analysis, global PALS was significantly and independently associated with paroxysmal AF. STE enables noninvasive quantification of LA dysfunction due to MR and paroxysmal AF. MR have a major negative impact on LA function. In patients with MR, the history of paroxysmal AF is associated to a further impair of LA myocardial reservoir function. |
| | |
Authors:
|
Matteo Cameli; Matteo Lisi; Francesca Maria Righini; Marta Focardi; Ottavio Alfieri; Sergio Mondillo |
Related Documents
:
|
8839279 - Magnetic resonance microscopy--a new tool for the toxicologic pathologist. 17510789 - Brain magnetic resonance in the diagnostic evaluation of mitochondrial encephalopathies. 15039589 - On the potential of normal-mode analysis for solving difficult molecular-replacement pr... 10835129 - Hydatid disease: radiologic and pathologic features and complications. 2408099 - Magnetic resonance imaging of the postoperative lumbar spine. 1523309 - Myometrial invasion by endometrial carcinoma: assessment with plain and gadolinium-enha... 15517549 - Upper level of the spina bifida defect: how good are we? 15489489 - Incremental nature of anterior eye grading scales determined by objective image analysis. 11733319 - Normal laryngeal ct findings after supracricoid partial laryngectomy. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-1 |
Journal Detail:
|
Title: The international journal of cardiovascular imaging Volume: - ISSN: 1875-8312 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-1 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100969716 Medline TA: Int J Cardiovasc Imaging Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Cardiovascular Diseases, University of Siena, Siena, Italy, cameli@cheapnet.it. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Methods of suicide used by children and adolescents.
Next Document: Animal Models of Dyssynchrony.