Document Detail

Left atrial appendage-flow velocity predicts cardioversion success in atrial fibrillation.
MedLine Citation:
PMID:  16498232     Owner:  NLM     Status:  MEDLINE    
Restoration of sinus rhythm by electrical cardioversion is a therapeutic option in appropriately selected patients with atrial fibrillation. It is important to determine predictors of electrical cardioversion outcome in patients with atrial fibrillation. Predictive value of clinical and conventional echocardiographic parameters for predicting cardioversion outcome is limited. The role of left atrial appendage (LAA) function, which may reflect left atrial contractile function, for prediction of cardioversion outcome remains unclear. We conducted a single center prospective study to evaluate the role of LAA function for prediction of cardioversion success in patients with atrial fibrillation. One hundred sixty three patients with atrial fibrillation underwent transthoracic and transesophageal echocardiography (TEE) before electrical cardioversion. LAA functions, including LAA peak flow velocity, LAA area and LAA ejection fraction, were examined. Cardioversion was successful in 133 patients and unsuccessful in 30 patients. Mean LAA peak emptying flow velocity was significantly higher in the patients with successful cardioversion than in those with unsuccessful cardioversion (0.34 +/- 0.14 vs 0.27 +/- 0.1 m/sec; p = 0.013). At multivariate logistic regression analysis, only LAA flow velocity (> 0.28 m/sec, odds ratio = 2.8 ; p = 0.03) proved to be an independent predictor of cardioversion success. LAA area (p = 0.18) and LAA ejection fraction (p = 0.52) were not different between successful and unsuccessful cardioversion groups. Therefore, measurement of LAA flow velocity provides valuable information for prediction of cardioversion outcome in patients with atrial fibrillation before TEE guided cardioversion.
Bahri Akdeniz; Ozer Badak; Nezihi Bariş; Ozgür Aslan; Onder Kirimli; Ozhan Göldeli; Sema Güneri
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Tohoku journal of experimental medicine     Volume:  208     ISSN:  0040-8727     ISO Abbreviation:  Tohoku J. Exp. Med.     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-02-24     Completed Date:  2006-04-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0417355     Medline TA:  Tohoku J Exp Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  243-50     Citation Subset:  IM    
Department of Cardiology, Dokuz Eylül University School of Medicine, Izmir, Turkey.
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MeSH Terms
Atrial Appendage / physiopathology*,  ultrasonography
Atrial Fibrillation / physiopathology*,  therapy*,  ultrasonography
Atrial Function, Left / physiology*
Blood Flow Velocity
Echocardiography, Doppler, Pulsed
Echocardiography, Transesophageal
Electric Countershock*
Logistic Models
Middle Aged
Predictive Value of Tests
Prospective Studies
Regional Blood Flow
Stroke Volume
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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