| Left adrenalectomy in varicocelized rats does not inhibit the development of varicocele-related physiologic alterations. | |
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MedLine Citation:
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PMID: 8401685 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the importance of retrograde adrenal metabolite flow for testicular function in a varicocelized animal model. MATERIALS AND METHODS: Partial occlusion of the left renal vein and ligation of the collateral vein between the left testicular and left common iliac veins was carried out on 14 Wistar rats (group A); same procedure plus adrenalectomy on 14 others (group B); seven sham operated (C) and seven with adrenalectomy alone (D). RESULTS: Groups A and B showed significant reduction in fertility, and also bilaterally in difference between testicular and abdominal temperatures, epididymal spermatozoal content and motility, and testicular weight at 12 weeks post-surgery. All values were nearly identical in groups A and B. CONCLUSIONS: Since left adrenalectomy did not ameliorate the effects of varicocele, it appears that retrograde flow of adrenal metabolite(s) may not be responsible for the harmful effect of (left) varicocele on fertility. |
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Authors:
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N Sofikitis; I Miyagawa |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International journal of fertility and menopausal studies Volume: 38 ISSN: 1069-3130 ISO Abbreviation: Int J Fertil Menopausal Stud Publication Date: 1993 Jul-Aug |
Date Detail:
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Created Date: 1993-10-26 Completed Date: 1993-10-26 Revised Date: 2010-03-24 |
Medline Journal Info:
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Nlm Unique ID: 9309760 Medline TA: Int J Fertil Menopausal Stud Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 250-5 Citation Subset: IM |
Affiliation:
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Tottori University School of Medicine, Department of Urology, Yonago, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Glands
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physiology* Adrenalectomy Analysis of Variance Animals Body Temperature Body Weight Disease Models, Animal Infertility, Male / etiology* Male Organ Size Rats Rats, Wistar Sperm Count Sperm Motility Spermatogenesis / physiology Testis / blood supply, pathology, physiopathology* Varicocele / complications, physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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