| Left Ventricular Systolic Dyssynchrony in Patients with Isolated Symptomatic Myocardial Bridge. | |
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MedLine Citation:
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PMID: 23036109 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Objectives: The impact of myocardial bridge (MB) on left ventricular (LV) systolic synchrony is insufficiently understood. Design: 35 subjects with isolated mid-left anterior descending artery (LAD) MB, preserved LV ejection fraction (LVEF>50%), and otherwise normal coronary angiogram were identified from 3607 patients underwent diagnostic coronary angiography and were evaluated by tissue Doppler imaging and real-time 3D echocardiography (RT3DE). Control subjects consisted of 26 age and sex matched coronary angiographically "normal" subjects. Results: MB patients were characterized by reduced early diastolic strain rate in LAD supplied apical segments (lateral and anterior), with prevalence of LV systolic dyssynchrony of 25.7% (9/35). MB patients were further classified by the medians of MB stenosis and length. For MB stenosis <52.5%, class I: length<17 mm (n=7), class II: length ≥17 mm (n=10); for stenosis≥ 52.5%, class III: length<17 mm (n=10), class IV: length ≥17 mm (n=8). Binary Logistic regression model revealed that higher MB lesion classification (odds ratio: 4.944, 95%CI 1.174-20.82, P<0.05) and hypertension (odds ratio: 15.32, 95%CI: 1.252-187.6, P<0.05) are statistically associated with LV systolic dyssynchrony, which was independent of LV mass. Conclusions: MB in the mid LAD is associated with myocardial dyssynchrony. Hypertensive individuals and those with more severe bridging (determined by length and stenosis) tend to have an increased incidence of dyssynchrony. |
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Authors:
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Wei Cai; Yan Dong; Xin Zhou; Shao-Bo Chen; Ji-Hong Zhao; Tie-Min Jiang; Yu-Ming Li |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-4 |
Journal Detail:
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Title: Scandinavian cardiovascular journal : SCJ Volume: - ISSN: 1651-2006 ISO Abbreviation: Scand. Cardiovasc. J. Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9708377 Medline TA: Scand Cardiovasc J Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
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