| Left ventricular function in gestational hypertension: serial echocardiographic study. | |
| | |
MedLine Citation:
|
PMID: 19763118 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Gestational hypertension (GH) is associated with hemodynamic changes, and alterations of systolic and diastolic left ventricular (LV) function. However, the magnitude and pattern of changes of different parameters of LV function and contractility in this patient population have not been fully clarified. METHODS: Thirty-five pregnant women with GH underwent three echocardiographic examinations, in second and third trimester of pregnancy, and 1 month after delivery. Twelve normotensive pregnant women served as gestational age-matched controls. Hemodynamic parameters and standard indexes of LV systolic and diastolic function were analyzed. Additionally, we have measured peak systolic velocity of mitral annulus (S'), end-systolic elastance (Ees), and early transmitral to early lengthening velocity of mitral annulus ratio (E/E') as parameters of longitudinal function, contractility, and filling, respectively. RESULTS: Women with GH had initially higher body weight, blood pressure, and heart rate (P < 0.005, P < 0.0001, and P = 0.011, respectively). Temporal analysis of different echocardiographic parameters revealed increase in wall thickness from baseline to second measurement, with consequential increase in LV mass in women with GH (P = 0.014 for septum, P = 0.010 for posterior wall, and P = 0.09 for LV mass). No significant changes of LV volumes, ejection fraction (EF), transmitral flow parameters, S', Ees, and E/E' were observed throughout the follow-up in both groups (P = nonsignificant for all). Importantly, pattern of changes was similar in both groups for all examined parameters (P = nonsignificant between groups, for all). CONCLUSIONS: It appears that changes of LV longitudinal function, filling, and contractility during pregnancy are not significant and not influenced by GH. |
| | |
Authors:
|
Alja Vlahović-Stipac; Vera Stankić; Zoran B Popović; Biljana Putniković; Aleksandar N Nesković |
Related Documents
:
|
3932708 - Effects of diltiazem and nitroglycerin on left ventricular diastolic properties in pati... 11356788 - Phase plane analysis of left ventricular hemodynamics. 7671378 - Determination of left ventricular chamber stiffness from the time for deceleration of e... 17928198 - Relationship between ventricular contractility and early diastolic intraventricular pre... 21115648 - Scale exponents of blood pressure and heart rate during autonomic blockade as assessed ... 8082358 - Cpap therapy via oronasal mask for obstructive sleep apnea. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-09-17 |
Journal Detail:
|
Title: American journal of hypertension Volume: 23 ISSN: 1941-7225 ISO Abbreviation: Am. J. Hypertens. Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2009-12-17 Completed Date: 2010-03-23 Revised Date: 2011-06-30 |
Medline Journal Info:
|
Nlm Unique ID: 8803676 Medline TA: Am J Hypertens Country: United States |
Other Details:
|
Languages: eng Pagination: 85-91 Citation Subset: IM |
Affiliation:
|
Department of Cardiology, Clinical Hospital Center Zemun, Belgrade, Serbia. avlahovic@hotmail.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Blood Pressure Body Weight Coronary Circulation Diastole Echocardiography* Female Follow-Up Studies Heart Rate Heart Septum / ultrasonography Humans Hypertension, Pregnancy-Induced / physiopathology*, ultrasonography* Mitral Valve / physiopathology, ultrasonography Myocardial Contraction Postpartum Period Pregnancy Pregnancy Trimester, Second Pregnancy Trimester, Third Systole Time Factors Ventricular Function, Left* Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The Coalition Against Major Diseases: developing tools for an integrated drug development process fo...
Next Document: Aldosterone contributes to blood pressure variance and to likelihood of hypertension in normal-weigh...