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Left Ventricular Assist Device as Bridge to Recovery for Anthracycline-Induced Terminal Heart Failure.
MedLine Citation:
PMID:  22521037     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Anthracycline treatments are hampered by dose-related cardiotoxicity, frequently leading to heart failure (HF) with a very poor prognosis. The authors report a case of a 19-year-old man developing HF after anthracycline treatment for Ewing sarcoma. Despite medical treatment, his condition deteriorated to terminal HF, leading to implantation of a mechanical left ventricular assist device (LVAD). His heart function recovered, allowing explantation of the device 14 months after implantation. Heart transplantation is often contraindicated in the first years after treatment for cancers, and LVAD as "bridge to recovery" may be warranted in similar patients.
Authors:
Jon M Appel; Kåre Sander; Peter B Hansen; Jacob E Møller; Anders Krarup-Hansen; Finn Gustafsson
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-22
Journal Detail:
Title:  Congestive heart failure (Greenwich, Conn.)     Volume:  -     ISSN:  1751-7133     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9714174     Medline TA:  Congest Heart Fail     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Affiliation:
From the Departments of CardiologyThoracic Surgery Thoracic Anesthesiology Oncology, Rigshopitalet, Copenhagen, Denmark.
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