| Left main stenting. | |
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MedLine Citation:
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PMID: 21415546 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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For several decades, based on clinical trials comparing coronary-artery bypass grafting (CABG) with medical therapy, bypass surgery has been regarded as the treatment of choice for patients with unprotected left main coronary artery (LMCA) disease. However, because of marked advancements in the techniques of percutaneous coronary intervention (PCI) with stenting and CABG and adjunctive pharmacologic therapy, reevaluation and review of current indications for optimal revascularization therapy for LMCA disease are required to determine the standard of care for these patients. The available current evidence suggests that the composite outcome of death, myocardial infarction and stroke is similar in patients with LMCA disease who are treated with either PCI with stenting or CABG, the only difference being the rate of repeat revascularization. Cumulative and emerging data from several extensive registries and a large clinical trial may have prompted many interventional cardiologists to select PCI with stenting as an alternative revascularization strategy for such patients. In addition, these data not only may change future guidelines, but support the need for prospective, large randomized trials comparing the 2 revascularization treatments. Finally, this evidence will change the current clinical practice of revascularization strategy for unprotected LMCA disease. |
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Authors:
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Seung-Jung Park; Duk-Woo Park |
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Publication Detail:
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Type: Journal Article; Review Date: 2011-03-10 |
Journal Detail:
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Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 75 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2011 |
Date Detail:
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Created Date: 2011-03-28 Completed Date: 2011-08-12 Revised Date: 2012-01-09 |
Medline Journal Info:
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Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
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Languages: eng Pagination: 749-55 Citation Subset: IM |
Copyright Information:
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All rights are reserved to the Japanese Circulation Society. |
Affiliation:
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Division of Cardiology, University of Ulsan College of Medicine, Asan Medical Center, 388-1 Poongnap-dong, Songpa-gu, Seoul, 138-736, Korea. sjpark@amc.seoul.kr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Balloon, Coronary
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methods*,
trends Animals Clinical Trials as Topic Coronary Artery Bypass / methods, trends Coronary Artery Disease / therapy* Humans Stents* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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