| Left atrial distensibility and left ventricular filling pressure in acute versus chronic severe mitral regurgitation. | |
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MedLine Citation:
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PMID: 20185021 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Echocardiograms and left ventricular (LV) filling pressure were obtained from 95 patients with chronic severe mitral regurgitation (MR) and 16 patients with acute severe MR. All patients underwent catheterization for preoperative examinations and LV filling pressure measurements. A total of 52 age-, gender- and co-morbidity-matched patients with negative coronary angiographic results served as the controls. Echocardiography, including assessment of left atrial (LA) distensibility, was performed simultaneously. LA distensibility correlated logarithmically with the LV filling pressure. However, the early-diastolic mitral inflow velocity divided by the early-diastolic mitral annular velocity (mitral E/E') correlated linearly with the LV filling pressure. Bivariate correlation analysis revealed that LV filling pressure correlated positively with the maximum and minimum indexed LA volume, as well as the E/E', but the LV filling pressure correlated negatively with LA distensibility, LA ejection fraction, and LV ejection fraction. However, the MR regurgitation volume was associated only with the maximum and minimum indexed LA volume. Receiver operating characteristic curve analysis indicated that LA distensibility was not inferior to E/E' for identifying a LV filling pressure >15 mm Hg. However, to identify acute severe MR, LA distensibility was superior to E/E'. In conclusion, LA distensibility, as is E/E', is a valuable diastolic parameter. In patients with severe MR, it offers adequate power to assess the LV filling pressure and to identify acute severe MR. |
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Authors:
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Shih-Hung Hsiao; Wei-Chun Huang; Ko-Long Lin; Kuan-Rau Chiou; Feng-You Kuo; Shih-Kai Lin; Chin-Chang Cheng |
Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The American journal of cardiology Volume: 105 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-26 Completed Date: 2010-04-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 709-15 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Cardiology, Department of Internal Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, People's Republic of China a841120@ms3.hinet.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Aged Aged, 80 and over Atrial Function, Right / physiology* Cardiac Volume / physiology Case-Control Studies Chronic Disease Compliance / physiology Female Humans Male Middle Aged Mitral Valve Insufficiency / complications, diagnosis, physiopathology* Predictive Value of Tests Ventricular Function, Left / physiology* Ventricular Pressure / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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