Document Detail


Lectin histochemistry and identification of O-acetylated sialoderivatives in the horse sublingual gland.
MedLine Citation:
PMID:  10340143     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study was aimed at characterizing the glycoconjugates produced by the horse sublingual gland and, in particular, at discriminating between the sialoderivatives by means of differential oxidation and saponification combined with lectin histochemistry and enzymatic degradation. The results showed a predominance of sialoglycoconjugates with beta-galactose as acceptor sugar in the salivary mucins produced by the sublingual gland. Besides being the most represented terminal residue, sialic acid was also expressed in a great variety of derivatives distinguishable on the basis of acceptor sugars to the penultimate beta-galactose as well as linkage and acetylation degree of the pyranose ring and the polyhydroxyl side chain. A role in the protection of mucous membranes from physical, chemical and pathogenic agents can be hypothesized for the horse sublingual mucins.
Authors:
P Scocco; G Menghi; P Ceccarelli; V Pedini
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of histochemistry : EJH     Volume:  43     ISSN:  1121-760X     ISO Abbreviation:  Eur J Histochem     Publication Date:  1999  
Date Detail:
Created Date:  1999-08-05     Completed Date:  1999-08-05     Revised Date:  2008-08-15    
Medline Journal Info:
Nlm Unique ID:  9207930     Medline TA:  Eur J Histochem     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  47-54     Citation Subset:  IM    
Affiliation:
Facoltà di Medicina Veterinaria, Università di Camerino, Italy.
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MeSH Terms
Descriptor/Qualifier:
Acetylation / drug effects
Animals
Female
Glycoconjugates / chemistry,  metabolism*
Histocytochemistry
Horses
Immunohistochemistry
Lectins / metabolism*
Male
Muramidase / metabolism
N-Acetylneuraminic Acid / analysis,  metabolism*
Neuraminidase / pharmacology
Sublingual Gland / metabolism*
alpha-L-Fucosidase / pharmacology
Chemical
Reg. No./Substance:
0/Glycoconjugates; 0/Lectins; 131-48-6/N-Acetylneuraminic Acid; EC 3.2.1.17/Muramidase; EC 3.2.1.18/Neuraminidase; EC 3.2.1.51/alpha-L-Fucosidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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