Document Detail

Lectin histochemistry of foamy cells in non-nervous tissues of feline sphingomyelinosis.
MedLine Citation:
PMID:  1723414     Owner:  NLM     Status:  MEDLINE    
Foamy cells in non-nervous tissues from a female Siamese cat with sphingomyelinosis were examined by lectin histochemistry. Many foamy cells, so-called Niemann-Pick cells, were found in the non-nervous tissues, such as liver, spleen, lung, kidney, adrenal gland, lymph node and tonsil. These cells were positive for Concanavalia ensiformis agglutinin, Ricinus communis agglutinin-I and wheat germ agglutinin. Storage materials in the foamy cells were different from those in affected cells of the nervous tissues. This study suggests that lectin histochemistry might be helpful in the diagnosis of sphingomyelinosis.
S Kamiya; T Yamagami; M Umeda; M Sugiyama; M Daigo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of comparative pathology     Volume:  105     ISSN:  0021-9975     ISO Abbreviation:  J. Comp. Pathol.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1992-03-10     Completed Date:  1992-03-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0102444     Medline TA:  J Comp Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  241-5     Citation Subset:  IM    
Department of Veterinary Anatomy, Nippon Veterinary and Zootechnical College, Tokyo, Japan.
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MeSH Terms
Carbohydrate Sequence
Carbohydrates / analysis*
Cat Diseases / metabolism,  pathology*
Foam Cells / chemistry*
Molecular Sequence Data
Niemann-Pick Diseases / metabolism,  pathology,  veterinary*
Organ Specificity
Palatine Tonsil / chemistry,  pathology
Staining and Labeling
Viscera / chemistry,  pathology
Reg. No./Substance:
0/Carbohydrates; 0/Lectins

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