Document Detail

Learning abilities of different inbred mouse strains--discriminated avoidance performance (author's transl)
MedLine Citation:
PMID:  7202525     Owner:  NLM     Status:  MEDLINE    
Avoidance discrimination (right-left) and discriminated avoidance performances of 15 inbred strains of mice were measured on 50 learning trials in each of two daily sessions with a specially designed automated Y-type maze apparatus. Each trial consisted of light and buzzer for five seconds as conditioned stimuli and electric shock for five seconds as an unconditioned stimulus. Intertrial intervals were 30 seconds. The subjects were ten animals of 60-75 days of age for each sex. Highly significant differences among the strains for all the learning performances and negative correlations between the avoidance and discriminating performances of the strains were observed. This suggests that different strains should be chosen for avoidance and for discrimination, when used in behavioral experiments. Among the strains RF/Ms, SWM/Ms and SWR/Ms were superior in avoidance, while C3H/HeMs, DBA/2 and DBAf/Lw were superior in discrimination. C3h/HeMs and C57BL/6HeMs had relatively high abilities for both learning tasks. D103/Ms had the lowest learning ability in avoidance, while SWM/Ms and SWR/Ms had the lowest in discrimination.
T Fujishima
Publication Detail:
Type:  English Abstract; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Jikken dobutsu. Experimental animals     Volume:  29     ISSN:  0007-5124     ISO Abbreviation:  Jikken Dobutsu     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-05-21     Completed Date:  1981-05-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  1256412     Medline TA:  Jikken Dobutsu     Country:  JAPAN    
Other Details:
Languages:  jpn     Pagination:  383-90     Citation Subset:  IM    
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MeSH Terms
Avoidance Learning*
Discrimination Learning*
Mice, Inbred A
Mice, Inbred AKR
Mice, Inbred BALB C
Mice, Inbred C3H
Mice, Inbred C57BL
Mice, Inbred CBA
Mice, Inbred DBA
Mice, Inbred Strains*
Species Specificity

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