Document Detail

Lead intoxication epidemic caused by ingestion of contaminated ground paprika.
MedLine Citation:
PMID:  8800188     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Report of a lead intoxication epidemic caused by ingestion of contaminated ground paprika. DESIGN: Retrospective study of case histories. SETTING: Institutional, toxicological and medical referral center for ambulatory and hospitalized care. PATIENTS: One hundred forty-one adults consumed paprika contaminated with lead tetroxide (red lead). INTERVENTIONS: Intravenous calcium disodium versenate (edetic acid). MAIN OUTCOME MEASURES: Measurement of zinc protoporphyrin:heme ratio of whole blood and the blood lead level. EDTA mobilization test. RESULTS: Fifty-three patients had symptoms and signs of lead poisoning. The most common clinical signs were colic and/or anemia. Twenty-six persons showed increased lead absorption without clinical symptoms and signs. Chelation therapy with calcium disodium versenate resulted in complete clinical recovery. CONCLUSION: Lead-contaminated ground paprika, not previously described as a cause of alimentary lead intoxication, may cause symptomatic poisoning.
T Kákosy; A Hudák; M Náray
Related Documents :
10795608 - Antidepressant treatment of posttraumatic stress disorder.
16837678 - Postexposure treatment with doxycycline for the prevention of tick-borne relapsing fever.
9329448 - Trauma and women: course, predictors, and treatment.
10442658 - Disability associated with psychiatric comorbidity and health status in bosnian refugee...
21407978 - P 300 event related potential in depression.
18403738 - Predicting long-term outcome after acute ischemic stroke: a simple index works in patie...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of toxicology. Clinical toxicology     Volume:  34     ISSN:  0731-3810     ISO Abbreviation:  J. Toxicol. Clin. Toxicol.     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-22     Completed Date:  1996-10-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8213460     Medline TA:  J Toxicol Clin Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-11     Citation Subset:  AIM; IM    
National Institute of Occupational Health, Budapest, Hungary.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antidotes / administration & dosage,  therapeutic use
Capsicum / poisoning*
Chelating Agents / administration & dosage,  therapeutic use
Cohort Studies
Disease Outbreaks*
Edetic Acid / administration & dosage,  therapeutic use
Enzyme Inhibitors / blood
Food Contamination*
Hungary / epidemiology
Injections, Intravenous
Lead / adverse effects*,  blood
Lead Poisoning / drug therapy,  epidemiology*
Middle Aged
Plants, Medicinal*
Protoporphyrins / blood
Retrospective Studies
Treatment Outcome
Reg. No./Substance:
0/Antidotes; 0/Chelating Agents; 0/Enzyme Inhibitors; 0/Protoporphyrins; 1314-41-6/lead tetroxide; 15442-64-5/zinc protoporphyrin; 60-00-4/Edetic Acid; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of calcium chloride and 4-aminopyridine therapy on desipramine toxicity in rats.
Next Document:  It's happening again--another diethylene glycol mass poisoning.