Document Detail


Lead intoxication epidemic caused by ingestion of contaminated ground paprika.
MedLine Citation:
PMID:  8800188     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: Report of a lead intoxication epidemic caused by ingestion of contaminated ground paprika. DESIGN: Retrospective study of case histories. SETTING: Institutional, toxicological and medical referral center for ambulatory and hospitalized care. PATIENTS: One hundred forty-one adults consumed paprika contaminated with lead tetroxide (red lead). INTERVENTIONS: Intravenous calcium disodium versenate (edetic acid). MAIN OUTCOME MEASURES: Measurement of zinc protoporphyrin:heme ratio of whole blood and the blood lead level. EDTA mobilization test. RESULTS: Fifty-three patients had symptoms and signs of lead poisoning. The most common clinical signs were colic and/or anemia. Twenty-six persons showed increased lead absorption without clinical symptoms and signs. Chelation therapy with calcium disodium versenate resulted in complete clinical recovery. CONCLUSION: Lead-contaminated ground paprika, not previously described as a cause of alimentary lead intoxication, may cause symptomatic poisoning.
Authors:
T Kákosy; A Hudák; M Náray
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of toxicology. Clinical toxicology     Volume:  34     ISSN:  0731-3810     ISO Abbreviation:  J. Toxicol. Clin. Toxicol.     Publication Date:  1996  
Date Detail:
Created Date:  1996-10-22     Completed Date:  1996-10-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8213460     Medline TA:  J Toxicol Clin Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  507-11     Citation Subset:  AIM; IM    
Affiliation:
National Institute of Occupational Health, Budapest, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Adult
Antidotes / administration & dosage,  therapeutic use
Capsicum / poisoning*
Chelating Agents / administration & dosage,  therapeutic use
Cohort Studies
Disease Outbreaks*
Edetic Acid / administration & dosage,  therapeutic use
Enzyme Inhibitors / blood
Female
Food Contamination*
Humans
Hungary / epidemiology
Injections, Intravenous
Lead / adverse effects*,  blood
Lead Poisoning / drug therapy,  epidemiology*
Male
Middle Aged
Plants, Medicinal*
Protoporphyrins / blood
Retrospective Studies
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antidotes; 0/Chelating Agents; 0/Enzyme Inhibitors; 0/Protoporphyrins; 1314-41-6/lead tetroxide; 15442-64-5/zinc protoporphyrin; 60-00-4/Edetic Acid; 7439-92-1/Lead

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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