| Layer-by-Layer Assembled Multilayer Films of Methoxypoly(ethylene glycol)-block-poly(α,L-glutamic acid) and Chitosan with Reduced Cell Adhesion. | |
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MedLine Citation:
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PMID: 21674805 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A methoxypoly(ethylene glycol)-block-poly(α,L-glutamic acid) (mPEGGA) diblock copolymer is synthesized. Using QCM measurements, it is shown that (CS/mPEGGA)(n) film construction takes place over two build-up stages (exponential-to-linear). UV-vis spectra reveal the regular increase of the multilayer film growth at different molecular weights of mPEGGA. Contact angle and surface morphology investigation prove that the hydrophilicity of CS/mPEGGA multilayer film-modified substrate becomes better and the surface becomes rough. Significantly reduced cell adhesion is observed on the CS/mPEGGA multilayer film coated surface. |
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Authors:
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Bin Cao; Shifeng Yan; Kunxi Zhang; Zhijiang Song; Xuesi Chen; Lei Cui; Jingbo Yin |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-6-15 |
Journal Detail:
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Title: Macromolecular bioscience Volume: - ISSN: 1616-5195 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-6-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101135941 Medline TA: Macromol Biosci Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
Affiliation:
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Department of Polymer Materials, Shanghai University, 20 Chengzhong Road, Jiading, Shanghai, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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