| Laxative-free CT colonography. | |
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MedLine Citation:
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PMID: 22167512 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objectives: To determine if the introduction of faecal tagging to CT colonography (CTC) made the examination easier to tolerate, or reduced the number of false positives.Methods: Our department changed bowel preparation for CT colonography from Picolax to Gastrografin only with a modified diet. Questionnaires were given to a subgroup of patients within these cohorts. The numbers of false positives were compared between two cohorts before and after this change. False positives were defined as lesions reported on CT that were not confirmed by subsequent endoscopic examination. Polyps were matched if they were in the same or adjacent segments, and were within 5 mm of the reported size.Results: 412 patients were identified from the Picolax cohort, and 116 from the Gastrografin cohort. 62 patients in each group completed questionnaires. Gastrografin produced less diarrhoea; 34% had five or more bowel motions in the previous day and night, compared with 77% for Picolax (p<0.001), although more patients found drinking it unpleasant compared with Picolax (85% reported drinking Picolax as "easy" vs 61% for Gastrografin; P0.002). Picolax produced more non-diagnostic examinations, although this difference was not statistically significant. There was not a significant reduction in the numbers of false positives (2 out of 112 for Gastrografin group, 14 out of 389 for the Picolax group; p = 0.54).Conclusion: Switching from Picolax to Gastrografin as a CTC preparation technique produced less diarrhoea, but did not reduce the number of false positives. |
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Authors:
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A Slater; M Betts; H D'Costa |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-13 |
Journal Detail:
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Title: The British journal of radiology Volume: - ISSN: 1748-880X ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0373125 Medline TA: Br J Radiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Radiology, John Radcliffe Hospital, Oxford, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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