Document Detail


Lateralization of temporal lobe foci: depth versus subdural electrodes.
MedLine Citation:
PMID:  11336899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Definitive localization of an epileptic focus correlates with a favorable outcome following epilepsy surgery. This study was undertaken to determine the incremental value of data yielded for surgical decision making when using subdural electrodes alone and in addition to depth electrodes for temporal lobe epilepsy. METHODS: Standardized placement for intracranial electrodes included: (1) longitudinal placement of bilateral temporal lobe depth electrodes; (2) bilateral subtemporal subdural strips; and (3) bilateral orbitofrontal subdural strips. Sixty-three events were randomly reviewed for: (1) subdural electrodes alone; and (2) depth electrodes in conjunction with subdural electrodes. RESULTS: Of the 63 seizures, 54 (85.7%) demonstrated congruent lateralization to ipsilateral subtemporal subdural strip electrodes (based on depth electrode localization) when subdural strip electrodes were utilized alone. In 3 of 22 patients, 7 seizures demonstrated 'false localization' on subdural electrode analysis alone when compared with depth recording and post-surgical outcome. For these 3 patients, retrospective review of neuroimaging demonstrated suboptimal ipsilateral placement of subtemporal subdural electrodes with the most mesial electrode lateral to the collateral sulcus. Four additional patients had suboptimal placement of subtemporal subdural electrodes. Two of these 4 patients had congruent localization with subdural electrodes to ipsilateral depth electrodes despite suboptimal placement. Subtemporal subdural electrodes accurately localized for all seizures from the mesial temporal lobe when the mesial electrodes of the subtemporal subdural strip recorded mesial to the collateral sulcus from the parahippocampal region. CONCLUSION: We conclude that although there are high concordance rates between subdural and depth electrodes, localization of seizure onset based on subdural strip electrodes alone may result in inaccurate focus identification with potential for possible suboptimal treatment of temporal lobe epilepsy. When subtemporal subdural electrodes provide recording from the parahippocampal region, there is accurate localization of the seizure focus. If suboptimal placement occurs lateral to the collateral sulcus, the electroencephalographer cannot make a definitive identification of the seizure focus.
Authors:
S Eisenschenk; R L Gilmore; J E Cibula; S N Roper
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology     Volume:  112     ISSN:  1388-2457     ISO Abbreviation:  Clin Neurophysiol     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-04     Completed Date:  2001-06-28     Revised Date:  2008-09-10    
Medline Journal Info:
Nlm Unique ID:  100883319     Medline TA:  Clin Neurophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  836-44     Citation Subset:  IM    
Affiliation:
Department of Neurology, University of Florida, University of Florida Brain Institute, 100 South Newell Drive, Room L3-100, Gainesville, FL 32601-0236, USA. eisensj@neurology.ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Brain Mapping / methods*
Cognition
Electrodes
Electroencephalography / instrumentation,  methods*
Epilepsy, Temporal Lobe / physiopathology*,  surgery
Functional Laterality / physiology*
Hippocampus / pathology,  physiopathology*
Humans
Magnetic Resonance Imaging
Reproducibility of Results
Temporal Lobe / pathology,  physiopathology*,  surgery
Video Recording

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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