Document Detail

Laterality associated with sexual dimorphism in the volume of the mouse hypogastric ganglion.
MedLine Citation:
PMID:  3758284     Owner:  NLM     Status:  MEDLINE    
The volume of the hypogastric ganglion was investigated in male, female, and prenatally androgen-exposed female newborn mice. Two milligram testosterone propionate was injected into pregnant ICR mice from days 14 to 16 of gestation. The volume of the ganglia on both sides in intact male neonates was significantly larger than that in female neonates. The volume of ganglia in testosterone-exposed females was significantly larger than those in intact females, but did not attain the male volume. In intact males, the ganglion on the left side was significantly larger than on the right. This left-right difference in the volume of the ganglia was not recognized in the intact or TP-exposed females. These results suggest that sex difference and lateralization of the volume of the hypogastric ganglion were highly dependent on the prenatal sex hormone environment.
Y Suzuki; Y Arai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Experimental neurology     Volume:  94     ISSN:  0014-4886     ISO Abbreviation:  Exp. Neurol.     Publication Date:  1986 Oct 
Date Detail:
Created Date:  1986-11-18     Completed Date:  1986-11-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370712     Medline TA:  Exp Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  241-5     Citation Subset:  IM    
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MeSH Terms
Animals, Newborn
Functional Laterality*
Ganglia, Autonomic / drug effects,  physiology*
Mice, Inbred ICR
Sex Characteristics*
Stomach / innervation
Testosterone / pharmacology
Reg. No./Substance:

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