| Laterality Preference and Cognition: Cross-Syndrome Comparison of Patients with Trisomy 21 (Down), del7q11.23 (Williams-Beuren) and del22q11.2 (DiGeorge or Velo-Cardio-Facial) Syndromes. | |
| | |
MedLine Citation:
|
PMID: 21455680 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
We report on a cross-syndrome comparison of hand, foot, eye and ear laterality in three groups of individuals with different genetic disorders (trisomy 21, del7q11.23, and del22q11.2) to test the relationship between atypical laterality and intellectual disability. These groups were compared to a group of typically developing persons. Hand, foot, eye and ear laterality was assessed using item tasks, conducted twice, and Bishop's card-reaching test. Ordering of the mean IQ score for each of the three groups was as follows: trisomy 21 < del7q11.23 < del22q11.2. We observed the same ordering as for IQ, particularly in mixed handedness, degree of laterality, hand and foot consistency. The existence of a cognitive threshold, below which lateral preference is atypical, advocates for a causal link between cognition and laterality in those with low IQ although unknown other factors underlying both could determine this association. |
| | |
Authors:
|
Michèle Carlier; Aude Gérard Desplanches; Nicole Philip; Silvia Stefanini; Stefano Vicari; Virginia Volterra; Christine Deruelle; Gene Fisch; Anne Lise Doyen; Anne Swillen |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-4-1 |
Journal Detail:
|
Title: Behavior genetics Volume: - ISSN: 1573-3297 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
|
Created Date: 2011-4-1 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0251711 Medline TA: Behav Genet Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Laboratoire de Psychologie Cognitive, UMR6146, Université Aix Marseille 1, CNRS, 3 Place Victor Hugo, Case D, 13331, Marseille Cedex 3, France, michele.carlier@univ-provence.fr. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A new concept of gentamicin loaded HAP/TCP bone substitute for prophylactic action: in vivo pharmaco...
Next Document: The immunoproteasomes regulate LPS-induced TRIF/TRAM signaling pathway in murine macrophages.