| Lateral transfer of genes from fungi underlies carotenoid production in aphids. | |
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MedLine Citation:
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PMID: 20431015 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carotenoids are colored compounds produced by plants, fungi, and microorganisms and are required in the diet of most animals for oxidation control or light detection. Pea aphids display a red-green color polymorphism, which influences their susceptibility to natural enemies, and the carotenoid torulene occurs only in red individuals. Unexpectedly, we found that the aphid genome itself encodes multiple enzymes for carotenoid biosynthesis. Phylogenetic analyses show that these aphid genes are derived from fungal genes, which have been integrated into the genome and duplicated. Red individuals have a 30-kilobase region, encoding a single carotenoid desaturase that is absent from green individuals. A mutation causing an amino acid replacement in this desaturase results in loss of torulene and of red body color. Thus, aphids are animals that make their own carotenoids. |
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Authors:
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Nancy A Moran; Tyler Jarvik |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Science (New York, N.Y.) Volume: 328 ISSN: 1095-9203 ISO Abbreviation: Science Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-30 Completed Date: 2010-05-11 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404511 Medline TA: Science Country: United States |
Other Details:
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Languages: eng Pagination: 624-7 Citation Subset: IM |
Affiliation:
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Department of Ecology and Evolutionary Biology, 1041 East Lowell Street, University of Arizona, Tucson, AZ 85721, USA. nancy.moran@yale.edu |
| Data Bank Information | |
Bank Name/Acc. No.:
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GENBANK/GU456379 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Aphids / genetics*, metabolism*, microbiology Carotenoids / analysis, biosynthesis*, genetics Crosses, Genetic Fungi / genetics Gene Duplication Gene Transfer, Horizontal* Genes, Fungal* Genes, Insect* Genome, Insect Heterozygote Molecular Sequence Data Mutation Oxidoreductases / genetics Phylogeny Pigmentation / genetics Pigments, Biological / chemistry Polymorphism, Genetic Sequence Analysis, DNA |
| Chemical | |
Reg. No./Substance:
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0/Pigments, Biological; 36-88-4/Carotenoids; 547-23-9/torulene; EC 1.-/Oxidoreductases; EC 1.14.99.-/phytoene dehydrogenase |
| Comments/Corrections | |
Comment In:
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Science. 2010 Apr 30;328(5978):574-5
[PMID:
20431000
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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