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Latent viral infection of cells in tissue culture. IV. Latent infection of L cells with psittacosis virus.
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MedLine Citation:
PMID:  13439113     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
By maintaining L cells in a balanced salt solution of inorganic salts and glucose (BSS) for 2 days or more, they are rendered incapable of supporting the growth of psittacosis virus (6BC), though it infects such cells and is present intracellularly for as long as 3 days in a non-infectious phase. The addition of an enriched medium to such a culture of cells at any time up to 4 days after infection results in the appearance of infectious virus within these cells, which multiplies and is released from the cells, providing the entire period of exposure of such cells to the BSS does not exceed 6 days, following which the cells die. A latent infection with psittacosis virus in a non-infectious phase has been established in a pure line of cells which possess properties of malignancy.
Authors:
H R MORGAN; J P BADER
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of experimental medicine     Volume:  106     ISSN:  0022-1007     ISO Abbreviation:  J. Exp. Med.     Publication Date:  1957 Jul 
Date Detail:
Created Date:  1957-12-01     Completed Date:  2002-05-01     Revised Date:  2012-04-16    
Medline Journal Info:
Nlm Unique ID:  2985109R     Medline TA:  J Exp Med     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  39-44     Citation Subset:  OM    
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MeSH Terms
Descriptor/Qualifier:
Chlamydophila psittaci / ethnology*
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Exp Med
ISSN: 0022-1007
ISSN: 1540-9538
Publisher: The Rockefeller University Press
Article Information
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Copyright © Copyright, 1957, by The Rockefeller Institute for Medical Research New York
Received Day: 26 Month: 2 Year: 1957
Print publication date: Day: 1 Month: 7 Year: 1957
Volume: 106 Issue: 1
First Page: 39 Last Page: 44
ID: 2136735
PubMed Id: 13439113

LATENT VIRAL INFECTION OF CELLS IN TISSUE CULTURE : IV. LATENT INFECTION OF L CELLS WITH PSITTACOSIS VIRUS
Herbert R. Morgan
John P. Bader
From the Louis A. Wehle Virus Research Laboratory of the Department of Bacteriology, The University of Rochester School of Medicine and Dentistry, Rochester, New York


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