Document Detail

Late vitamin K deficiency bleeding after intramuscular prophylaxis at birth: a case report.
MedLine Citation:
PMID:  19177046     Owner:  NLM     Status:  MEDLINE    
We report the case of a 6-week-old female who presented an intracranial hemorrhage due to late vitamin K deficiency bleeding (VKDB). No other evident bleeding sites were present at the moment of diagnosis. Intramuscular vitamin K (1 mg) was administered at birth. She was exclusively breast-fed. No other risk factors for VKDB were detected. Low levels of vitamin K-dependent coagulation factors and their normalization after vitamin K administration confirmed the diagnosis of late VKDB. The present case suggests potential risks related to a single dose of intramuscular vitamin K at birth.
M Ciantelli; L Bartalena; M Bernardini; P Biver; F Chesi; A Boldrini; E Sigali
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  29     ISSN:  1476-5543     ISO Abbreviation:  J Perinatol     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-01-29     Completed Date:  2009-06-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  168-9     Citation Subset:  IM    
Division of Neonatology, University of Pisa, Pisa, Italy.
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MeSH Terms
Age of Onset
Antifibrinolytic Agents / administration & dosage*
Infant, Newborn
Injections, Intramuscular
Intracranial Hemorrhages / etiology*
Treatment Outcome
Vitamin K / administration & dosage*
Vitamin K Deficiency / complications*
Reg. No./Substance:
0/Antifibrinolytic Agents; 12001-79-5/Vitamin K

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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