Document Detail

Late ventricular potentials and heavy drinking.
MedLine Citation:
PMID:  9326991     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To assess the effects of chronic drinking on detection of low amplitude signals, and to determine the relation between late ventricular potentials (LVP) and liver biopsy findings. DESIGN: Prospective study. SETTING: General hospital. PATIENTS: 41 consecutive chronic alcoholics without known pre-existing heart disease. METHODS: About four days after each patient's last alcoholic drink, ECG, echocardiography, signal averaged electrocardiogram, liver biopsy, and blood tests were performed. RESULTS: Twenty eight per cent of patients had evidence of LVP. There was a correlation between the percentage of steatosis of the hepatic biopsy and the amplitude of the last 40 ms of average QRS (P = 0.04), the duration of the terminal low amplitude QRS signal (P = 0.05), and the number of positive criteria of late potentials (P = 0.02). CONCLUSIONS: Chronic drinking sufficient to cause steatosis is associated with positive findings on the signal averaged ECG.
G Pochmalicki; M Genest; H Jibril
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  78     ISSN:  1355-6037     ISO Abbreviation:  Heart     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-10-22     Completed Date:  1997-10-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  163-5     Citation Subset:  AIM; IM    
Service de Cardiologie, C.H.G. Léon Binet, Provins, France.
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MeSH Terms
Alcoholism / pathology,  physiopathology*
Fatty Liver / pathology,  physiopathology
Liver / pathology
Middle Aged
Prospective Studies
Signal Processing, Computer-Assisted*
Ventricular Dysfunction / pathology,  physiopathology*

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