Document Detail


Late thromboembolic events after circumferential pulmonary vein ablation of atrial fibrillation.
MedLine Citation:
PMID:  19937096     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Catheter ablation can restore sinus rhythm in selected patients with atrial fibrillation (AF), but its preventive function for thromboembolic events (TE) is still underdetermined. METHODS: We retrospectively studied 520 consecutive patients with AF who were referred for circumferential pulmonary vein ablation. The incidence of late TE was investigated, and the predictors of late TE were identified from analysis of the basic clinical variables of patients with late TE. RESULTS: Eight (1.5%) patients experienced late TE during 28+/-8 months follow-up. When TE occurred, most (6/8, 75%) patients were documented with recurrence episode. The recurrence of AF was more frequent in patients with late TE than patients without late TE (75.0% vs 30.5%, P=0.007). Multivariate logistic regression analysis identified that all risk factors, including all clinical variants prior ablation and the CHADS2 score, were not related to late TE but the presence of recurrence was the only predictor of late TE (odds ratio, 5.542; 95% confidence interval [1.416-45.013], P=0.019). CONCLUSIONS: Our study demonstrates a strong relationship between the recurrence after ablation and TE post-operation and supports the proposal that free of recurrence is an indication for discontinuation of anticoagulation after ablation.
Authors:
Hailong Tao; Changsheng Ma; Jianzeng Dong; Xingpeng Liu; Deyong Long; Ronghui Yu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing     Volume:  27     ISSN:  1572-8595     ISO Abbreviation:  J Interv Card Electrophysiol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-03-18     Completed Date:  2010-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9708966     Medline TA:  J Interv Card Electrophysiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  33-9     Citation Subset:  IM    
Affiliation:
Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.
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MeSH Terms
Descriptor/Qualifier:
Atrial Fibrillation / epidemiology*,  surgery*
Catheter Ablation / statistics & numerical data*
China / epidemiology
Comorbidity
Female
Humans
Incidence
Male
Middle Aged
Postoperative Complications / epidemiology*
Pulmonary Veins / surgery*
Retrospective Studies
Risk Assessment
Risk Factors
Thromboembolism / epidemiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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