Document Detail


Late termination of pregnancy and foetal reduction for foetal anomaly.
MedLine Citation:
PMID:  20350838     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
Late termination of pregnancy is a relatively rare procedure accounting for approximately 1% of all registered terminations in England and Wales; however, with improving detection rates for foetal anomalies, this number is increasing. Surgical dilation and evacuation (D&E) appears to be a safe and cost-effective procedure as long as the clinical expertise exists to provide this service. Medical termination appears equally safe and is best undertaken with the combined use of mifepristone and misoprostol. Foeticide, when required, should be performed from 22 weeks' gestation using strong KCl administered either by cardiocentesis or by cordocentesis. All women should be offered a post-mortem and any other appropriate investigation to allow accurate counselling regarding future pregnancies. The issue of late selective foetal reduction for foetal abnormality is complicated by the need to balance the risks to the healthy co-twin of expectant management versus selective termination.
Authors:
Raffaele Napolitano; Basky Thilaganathan
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Publication Detail:
Type:  Journal Article     Date:  2010-03-29
Journal Detail:
Title:  Best practice & research. Clinical obstetrics & gynaecology     Volume:  24     ISSN:  1532-1932     ISO Abbreviation:  Best Pract Res Clin Obstet Gynaecol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101121582     Medline TA:  Best Pract Res Clin Obstet Gynaecol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  529-37     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Ltd. All rights reserved.
Affiliation:
St. Georges University of London, Cranmer Terrace, UK.
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