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Late stent fracture - A potential role of left ventricular dilatation.
MedLine Citation:
PMID:  24954989     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Coronary stent fracture is an under-recognized event but one that has been reported frequently in the drug-eluting stent era. Most reported cases of stent fracture occurred within days to two years after implantation, and are related to stent thrombosis and restenosis.
CASE REPORT: Presentation of a 69-year-old male with a history of arterial hypertension and previous percutaneous coronary intervention (PCI), and with implantation of three overlapping drug-eluting stents (DES) on proximal-to-middle left anterior descending artery (LAD). At five-year outpatient evaluation, the patient was found to have a new left bundle branch block associated with mild elevation in Troponin-I value and severe left ventricular dysfunction. The patient recovered as non ST-segment elevation myocardial infarction (NSTEMI) and consequently a new coronary angiography showed total occlusion of proximal LAD with multiple stent fracture. Here we discuss the role of left ventricular dilatation as a contributing factor to late drug-eluting stent fracture.
CONCLUSION: Different anatomical coronary settings have been described as predisposing factors to stent fracture. Consequently, the remodeling of the left ventricle, together with the rise in diastolic pressure, may have affected the shear stress of LAD stents by increasing mechanical forces produced in the diastolic phase on the epicardial vessel. In addition, left ventricular enlargement could have increased the elongation forces on the stent frames by altering the curvature of the stent. All predisposing factors of stent fracture, including coronary and left ventricular issues, need to be considered before stent implantation to avoid stent fracture and clinical sequelae.
Authors:
Ahmed Al Mamary; Gilberto Dariol; Massimo Napodano
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Publication Detail:
Type:  Journal Article     Date:  2014-02-10
Journal Detail:
Title:  Journal of the Saudi Heart Association     Volume:  26     ISSN:  1016-7315     ISO Abbreviation:  J Saudi Heart Assoc     Publication Date:  2014 Jul 
Date Detail:
Created Date:  2014-06-23     Completed Date:  2014-06-23     Revised Date:  2014-06-25    
Medline Journal Info:
Nlm Unique ID:  9887261     Medline TA:  J Saudi Heart Assoc     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  162-5     Citation Subset:  -    
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