Document Detail

Late selective termination of fetal abnormalities in twin pregnancies: a multicentre report.
MedLine Citation:
PMID:  8968238     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the outcome of late selective fetal termination based on combined data from eight tertiary perinatal centres. DESIGN: Israeli law requires institutional committee approval for pregnancy termination. Moreover, after 24 weeks only a district superior committee can approve the termination. A total of 36 bichorionic twin pregnancies who underwent selective fetal termination after 24 complete gestational weeks were identified in eight Israeli centres. RESULTS: In 23 women (63.9%) the indication for selective termination was structural anomaly, and in 13 (36.1%) the indication was chromosomal abnormality. The mean gestational age at the time of diagnosis was 24.1 +/- 1.9 weeks. The termination procedure was performed at a mean gestational age of 25.5 +/- 2.0 weeks (median 25, range 24-33 weeks). There was one case of immediate procedure-related complication (i.e. amnionitis) and the unaffected infant died, which was the only perinatal death in this series. No evidence of coagulopathy was reported. Only five women (13.8%) delivered before 34 completed weeks. The mean gestational age at delivery was 36.9 +/- 2.9 weeks (28-41 weeks), and the mean procedure-to-delivery interval was 11.8 +/- 3.2 weeks (median 13, range 3-17 weeks). CONCLUSIONS: Late (> 24 weeks) selective termination in twin pregnancies is associated with favourable perinatal outcome of the healthy twin. In countries where the law permits late pregnancy termination, the parents should be informed of that possibility.
S Lipitz; E Shalev; I Meizner; S Yagel; Z Weinraub; A Jaffa; J Shalev; R Achiron; E Schiff
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  103     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-01-27     Completed Date:  1997-01-27     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1212-6     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynaecology, Chaim Sheba Medical Center, Tel Hashomer & Sackler School of Medicine, Tel Aviv University, Israel.
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MeSH Terms
Birth Weight
Congenital Abnormalities / therapy*
Gestational Age
Maternal Age
Pregnancy Outcome
Pregnancy Reduction, Multifetal*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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