| Late revascularization reduces mortality in survivors of myocardial infarction. | |
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MedLine Citation:
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PMID: 10423665 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In survivors of acute myocardial infarction, the restoration of antegrade flow in the infarct-related coronary artery may improve prognosis by a mechanism that is independent of its influence on left ventricular systolic performance. Furthermore, survival may be improved even when antegrade flow is restored days or even weeks after the acute event. In several retrospective studies of survivors of infarction, we and others have shown a) that long-term survival is substantially better in those with-as opposed to those without-antegrade flow in the infarct-related coronary artery, and b) that the mechanical restoration of flow in an occluded infarct-related artery (accomplished with balloon angioplasty or bypass grafting) markedly improves long-term survival. The late restoration of antegrade flow in the infarct-related artery appears to render the so-called border zone of infarction less electrically unstable, thereby reducing the likelihood of ventricular tachyarrhythmias and sudden death. |
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Authors:
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L D Hillis; J E Cigarroa; R A Lange |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiology in review Volume: 7 ISSN: 1061-5377 ISO Abbreviation: Cardiol Rev Publication Date: 1999 May-Jun |
Date Detail:
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Created Date: 1999-12-02 Completed Date: 1999-12-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9304686 Medline TA: Cardiol Rev Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 144-8 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine (Cardiovascular Division), University of Texas Southwestern Medical Center, Dallas, Texas 75235-9047, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cause of Death Coronary Circulation* / physiology* Death, Sudden, Cardiac / epidemiology, prevention & control Female Humans Male Middle Aged Myocardial Infarction / mortality, physiopathology, therapy* Myocardial Revascularization* Survival Rate Tachycardia, Ventricular / mortality, physiopathology, therapy Ventricular Function, Left / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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