Document Detail


Late recurrence of minimal lesion nephrotic syndrome.
MedLine Citation:
PMID:  6691659     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Nephrotic syndrome recurred in 16 patients who had been free of the disease for an interval of 4 to 25 years. Their initial illness began in childhood and responded to adrenocorticosteroid therapy; in 10 patients it was associated with few changes on light microscopic examination of kidney biopsy specimens. The late recurrence also responded to steroids, and in only 1 patient did low-grade proteinuria persist after treatment. Renal biopsy specimens taken from 8 patients during late recurrence showed minimal-change nephrotic syndrome in 7 and focal segmental glomerulosclerosis in 1. Renal function remained normal in all patients. The late recurrence of minimal-change nephrotic syndrome has most of the features of that syndrome seen in the more typical childhood age group and should be managed similarly.
Authors:
C Pru; C M Kjellstrand; R A Cohn; R L Vernier
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Annals of internal medicine     Volume:  100     ISSN:  0003-4819     ISO Abbreviation:  Ann. Intern. Med.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-02-14     Completed Date:  1984-02-14     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372351     Medline TA:  Ann Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  69-72     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adrenal Cortex Hormones / therapeutic use
Biopsy
Child
Child, Preschool
Drug Resistance
Female
Humans
Infant
Male
Nephrosis, Lipoid / pathology,  physiopathology*
Pregnancy
Pregnancy Complications
Recurrence
Respiratory Tract Infections / complications
Time Factors
Grant Support
ID/Acronym/Agency:
AI10704/AI/NIAID NIH HHS; AM07087/AM/NIADDK NIH HHS
Chemical
Reg. No./Substance:
0/Adrenal Cortex Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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