Document Detail


Late-preterm birth and neonatal morbidities: population-level and within-family estimates.
MedLine Citation:
PMID:  25481078     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE: The objective of this study was to compare two salient neonatal outcomes-respiratory disorders and hyperbilirubinemia-between late-preterm (34-36 weeks) and full-term (37-41 weeks) singleton infants both at the population level and within families.
METHODS: Analyses were based on natality data on all births in the state of New Jersey from 1996 to 2006 linked to newborn hospital discharge records. For population-level models, logistic regression analyses were conducted to estimate unadjusted and adjusted differences in outcomes by gestational age. For within-family analyses, unadjusted and adjusted logistic fixed-effects models were estimated with the latter including factors that differed across births to the same mother.
RESULTS: Late-preterm birth increased the odds of a neonatal respiratory condition by more than fourfold (odds ratio, 4.08-4.53) and of neonatal hyperbilirubinemia by more than fivefold (odds ratio, 5.11-5.93) even when comparing births to the same mother and controlling for demographic and economic, behavioral, and obstetric factors that may have changed across pregnancies.
CONCLUSIONS: Based on population-level and within-family models, this study provides the strongest evidence to date that late-preterm birth is an important risk factor for adverse neonatal outcomes that other studies have found are associated with cognitive and behavioral disorders in childhood.
Authors:
Nancy E Reichman; Julien O Teitler; Sophie Moullin; Barbara M Ostfeld; Thomas Hegyi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-31
Journal Detail:
Title:  Annals of epidemiology     Volume:  -     ISSN:  1873-2585     ISO Abbreviation:  Ann Epidemiol     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-12-7     Completed Date:  -     Revised Date:  2014-12-8    
Medline Journal Info:
Nlm Unique ID:  9100013     Medline TA:  Ann Epidemiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
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