Document Detail

Late peripheral stent thrombosis due to stent fracture, vigorous exercise and hyporesponsiveness to clopidogrel.
MedLine Citation:
PMID:  22403133     Owner:  NLM     Status:  MEDLINE    
Late peripheral arterial stent thrombosis usually occurs due to haemodynamically relevant in-stent restenosis. However, late stent thrombosis may be multicausal. We report here the well-documented case of a 69-year-old man with acute thrombosis of the stented superficial femoral artery after a long-distance bicycle tour. Catheter-directed thrombolysis revealed a residual stenosis located at a stent fracture site. In addition, platelet function tests revealed an inadequate platelet response to clopidogrel. In conclusion, stent fracture, strenuous exercise and hyporesponsiveness to clopidogrel may have contributed to the development of late peripheral stent thrombosis.
Birgit Linnemann; Axel Thalhammer; Zsuzsanna Wolf; Vanessa Tirneci; Thomas J Vogl; And Edelgard Lindhoff-Last
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  VASA. Zeitschrift für Gefässkrankheiten     Volume:  41     ISSN:  0301-1526     ISO Abbreviation:  VASA     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-03-09     Completed Date:  2012-05-04     Revised Date:  2012-10-19    
Medline Journal Info:
Nlm Unique ID:  0317051     Medline TA:  Vasa     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  136-44     Citation Subset:  IM    
Division of Vascular Medicine, Department of Internal Medicine, J.W. Goethe University Hospital, Frankfurt/Main, Germany.
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MeSH Terms
Angioplasty / adverse effects*,  instrumentation*
Arterial Occlusive Diseases / therapy*
Constriction, Pathologic
Drug Resistance
Femoral Artery* / radiography
Platelet Aggregation Inhibitors / adverse effects*
Platelet Function Tests
Prosthesis Design
Prosthesis Failure*
Risk Factors
Thrombolytic Therapy
Thrombosis / blood,  etiology*,  radiography,  therapy
Ticlopidine / adverse effects,  analogs & derivatives*
Treatment Outcome
Reg. No./Substance:
0/Platelet Aggregation Inhibitors; 55142-85-3/Ticlopidine; 90055-48-4/clopidogrel

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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