Document Detail

Late onset of cholesterol crystal embolism after thrombolysis for cerebral infarction.
MedLine Citation:
PMID:  20453403     Owner:  NLM     Status:  MEDLINE    
A 73-year-old man was admitted to our hospital because of bilateral foot pain. He was treated with thrombolysis for cerebral infarction about 5 months ago. Anticoagulants had not been used because of hemorrhagic infarction. The pulses of bilateral pedal arteries were palpable, but cyanosis was present in the bilateral toes. Laboratory data indicated azotemia and eosinophilia. Magnetic resonance imaging revealed multiple plaques of the thoracic and abdominal aorta, one of which was ulcerated. Skin biopsy proved the diagnosis of cholesterol crystal embolism (CCE). Because no invasive vascular procedure was performed, we assumed that CCE in this patient was related to thrombolysis. We should be cautious for late onset of CCE after thrombolysis.
Kotaro Oe; Tsutomu Araki; Akikatsu Nakashima; Katsuaki Sato; Tetsuo Konno; Masakazu Yamagishi
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-04-30
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  49     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-10     Completed Date:  2010-08-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  833-6     Citation Subset:  IM    
Division of Internal Medicine, Saiseikai Kanazawa Hospital.
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MeSH Terms
Adrenal Cortex Hormones / administration & dosage
Alprostadil / therapeutic use
Angiography / methods
Biopsy, Needle
Cerebral Infarction / drug therapy*
Drug Therapy, Combination
Embolism, Cholesterol / diagnosis,  drug therapy,  etiology*
Follow-Up Studies
Magnetic Resonance Imaging / methods
Risk Assessment
Severity of Illness Index
Thrombolytic Therapy / adverse effects*,  methods
Time Factors
Tissue Plasminogen Activator / adverse effects*,  therapeutic use
Toes / pathology*,  physiopathology
Treatment Outcome
Reg. No./Substance:
0/Adrenal Cortex Hormones; 745-65-3/Alprostadil; EC Plasminogen Activator

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