Document Detail

Late onset angiotensin-converting enzyme induced angioedema: case report and review of the literature.
MedLine Citation:
PMID:  10024785     Owner:  NLM     Status:  MEDLINE    
Angiotensin-converting enzyme inhibitors (ACEI) such as enalapril, captopril, and lisinopril are well established as effective treatments of arterial hypertension and congestive heart failure. They are widely used and generally well tolerated. Angioedema is a rare but serious adverse effect of ACEI therapy. Most frequently, edema involves the face, oral cavity, and the glossopharyngeal or glottic area. Visceral edema induced by ACEI has also occurred. Life threatening and even fatal cases associated with ACEI have been reported. Although angioedema typically occurs within the first weeks of ACEI therapy, some cases with latencies of several months to years have been reported. This paper reports a case of late onset and recurrent angioedema in a patient treated with lisinopril for hypertension. A discussion of ACEI angioedema follows.
X Guo; L Dick
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of the Oklahoma State Medical Association     Volume:  92     ISSN:  0030-1876     ISO Abbreviation:  J Okla State Med Assoc     Publication Date:  1999 Feb 
Date Detail:
Created Date:  1999-03-04     Completed Date:  1999-03-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7503043     Medline TA:  J Okla State Med Assoc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  71-3     Citation Subset:  IM    
St. Anthony Hospital, Oklahoma City, USA.
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MeSH Terms
Angioedema / chemically induced*,  physiopathology
Angiotensin-Converting Enzyme Inhibitors / adverse effects*,  therapeutic use
Hypertension / drug therapy
Lisinopril / adverse effects*,  therapeutic use
Middle Aged
Risk Factors
Time Factors
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 83915-83-7/Lisinopril

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