Document Detail


Late onset Rasmussen's encephalitis with triple pathology.
MedLine Citation:
PMID:  19800797     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rasmussen's encephalitis is a devastating illness characterized by intractable focal seizures due to chronic localised encephalitis. We report on a rare variant of delayed onset Rasmussen's encephalitis with triple pathology. A 27-year-old male, who was initially diagnosed with seizures when he was 16 years old, presented with focal seizures that became refractory to multiple anticonvulsants. Multiple investigations, including subdural electrode monitoring, revealed foci of onset in the right frontotemporal region. The patient underwent right front-temporal lobectomy. Post-operatively, the seizures became more severe and he developed new epilepsia partialis continua. Treatment with intravenous immunoglobulin was unsuccessful. He subsequently underwent a right hemispherectomy that rendered him seizure free. The three pathologies identified were old ischemic changes, type II cortical dysplasia and stage II Rasmussen's encephalitis.
Authors:
J Y Cheong; C Wong; A Bleasel; W Varikatt; T Ng; M A Dexter
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-10-02
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  16     ISSN:  1532-2653     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-05-11     Completed Date:  2010-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  1677-81     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery Westmead Hospital, Hawksbury Road, Westmead, New South Wales 2145, Australia. Santiago-james@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Cognition Disorders / etiology
Encephalitis / complications,  pathology*,  radionuclide imaging
Epilepsy / etiology
Frontal Lobe / pathology,  radionuclide imaging
Humans
Lymphocytes / pathology
Magnetic Resonance Imaging / methods
Male
Neurons / pathology
Sclerosis / etiology,  pathology
Temporal Lobe / pathology,  radionuclide imaging
Tomography, Emission-Computed, Single-Photon / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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