Document Detail

Late obstruction after subureteral collagen injection.
MedLine Citation:
PMID:  16685623     Owner:  NLM     Status:  MEDLINE    
We present a case with distal ureteral obstruction after a single subureteral collagen injection. Postnatally, the girl presented with bilateral vesicoureteral reflux (VUR). At one year of age, a bilateral subureteral collagen injection was carried out. Postoperatively, the girl was followed up regularly and showed no pathological findings. But three years later, hydronephrosis with a distal ureteral obstruction on the right side was found. An ureteral reimplantation was performed on that side and the histological finding was a ureteral stenosis, consisting of collagen with a knotty sclerosis and a histiocytic and granulomatous reaction. This is the first case with a late obstruction at the ureteral orifice three years after a single collagen injection. We found an inflammatory reaction against the collagen, which led to a sclerosis of the implant. Further surveillance of patients after subureteral injections should focus on this kind of complication.
H-J Kirlum; M Stehr; H-G Dietz
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift für Kinderchirurgie     Volume:  16     ISSN:  0939-7248     ISO Abbreviation:  Eur J Pediatr Surg     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-05-10     Completed Date:  2006-09-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9105263     Medline TA:  Eur J Pediatr Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  133-4     Citation Subset:  IM    
Kinderchirurgische Klinik, Dr. von Haunersches Kinderspital, Ludwig-Maximilians-Universität München, München, Germany.
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MeSH Terms
Collagen / administration & dosage,  adverse effects*
Foreign-Body Reaction / etiology*,  pathology
Hydronephrosis / etiology
Infant, Newborn
Prostheses and Implants / adverse effects*
Ureteral Obstruction / etiology*,  pathology
Vesico-Ureteral Reflux / therapy*
Reg. No./Substance:

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