Document Detail

Late normalisation of uterine artery velocimetry in high risk pregnancy.
MedLine Citation:
PMID:  11267718     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test whether late normalisation of abnormal uterine velocimetry is a favourable prognostic factor in high risk pregnancies. STUDY DESIGN: Uterine artery colour Doppler velocimetry was performed at 24, 28-30 and 32-34 weeks in 282 high risk pregnancies treated with low dose aspirin. RESULTS: 88 patients had abnormal waveforms at 24 weeks and 77 delivered after the second assessment at 28 weeks. Of these, 38 (49%) had a normalisation of Doppler indices by 34 weeks. Compared with the persistently abnormal Doppler group, these patients delivered fewer small for gestational age babies (5/38 versus 26/39; p=0.0001) and had less gestational hypertension without proteinuria (3/38 versus 15/39; p=0.004). No patients with preeclampsia or other severe complications of pregnancy were observed in the normalised group. CONCLUSIONS: Although abnormal uterine artery velocimetry at 24 weeks is predictive of adverse pregnancy outcome, nearly half have late normalisation of the Doppler indices and a better perinatal outcome. Persistently abnormal waveforms are related to the worst pregnancy outcome.
M Soregaroli; A Valcamonico; L Scalvi; L Danti; T Frusca
Related Documents :
9354888 - Cordocentesis using the combined technique; needle guide-assisted and free-hand.
18254148 - Is three-dimensional power doppler ultrasound useful in the assessment of placental per...
1566768 - Endothelium-derived relaxing factor and indomethacin-sensitive contracting factor alter...
1863128 - Absent or reversed end diastolic flow velocity in the umbilical artery and necrotising ...
6359068 - Diabetes mellitus and pregnancy.
6201928 - Platelet sensitivity to a prostacyclin analogue in normal and pathological pregnancy.
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  95     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-03-27     Completed Date:  2001-07-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  42-5     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Brescia, Piazzale Spedali Civili 1, 25100, Brescia, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Arteries / physiology,  ultrasonography
Aspirin / administration & dosage
Blood Flow Velocity
Dose-Response Relationship, Drug
Fetal Death
Hypertension / physiopathology
Infant, Newborn
Infant, Small for Gestational Age
Pre-Eclampsia / physiopathology
Predictive Value of Tests
Pregnancy Complications, Cardiovascular / drug therapy,  physiopathology*
Pregnancy, High-Risk / physiology*
Ultrasonography, Doppler, Color / methods
Ultrasonography, Prenatal / methods
Uterus / blood supply*,  ultrasonography
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Non-invasive early prenatal diagnosis using fluorescent in situ hybridization on transcervical cells...
Next Document:  The effect of 17beta-estradiol on isolated omental arteries from preeclamptic women.