| Late modifications of cephalic circulation in head x-irradiated rats. | |
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MedLine Citation:
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PMID: 986667 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A non-invasive and quantitative radioisotope method was applied to the assessment of late cephalic circulatory changes occurring 12 and 21 months after head irradiation at 500, 1000 or 1500 R in rats of two inbred strains. Analysis of the results concerning the tracer circulatory mean transit-time (t) as well as those of two indices measuring respectively the cephalic blood volume (VH) and the cephalic blood flow (FH), led us to conclude that: -- the radiation-induced late changes in cephalic circulation are more relevant to a reduction of the volume of blood flowing in the head than to a reduction of its rate -- even a dose as low as 500 R induces such a late effect but the delay is longer than one year -- a depression of the cardiac output can be an additional very late consequence of head irradiation -- there is an influence of the rat strain on the temporal development of the late cephalic circulatory changes. |
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Authors:
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A Keyeux |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiation and environmental biophysics Volume: 13 ISSN: 0301-634X ISO Abbreviation: Radiat Environ Biophys Publication Date: 1976 Jul |
Date Detail:
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Created Date: 1976-11-01 Completed Date: 1976-11-01 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0415677 Medline TA: Radiat Environ Biophys Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 125-35 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Head / blood supply, radiation effects* Radiation Effects* Rats Rats, Inbred Strains Regional Blood Flow / radiation effects Time Factors X-Rays |
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