Document Detail


Late left ventricular color M-mode Doppler in the assessment of diastolic dysfunction in patients with dilated cardiomyopathy.
MedLine Citation:
PMID:  16153525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The ratio of early (Ep) to late (Ap) color M-mode Doppler flow propagation through the left ventricle helps in the differentiation between normal and pseudonormal (PSN) filling pattern in patients with preserved systolic function. We studied the value of this index in the assessment of diastolic dysfunction for patients with reduced left ventricular systolic function. We studied 80 patients with nonischemic dilated cardiomyopathy and 50 control subjects. According to echocardiography 53 patients had abnormal relaxation and 27 had PSN pattern. Patients had reduced Ep (P < .001) and Ep/Ap ratio (P < .001) and increased Ap (P = .001) compared to controls. Binary logistic regression analysis showed that Ep followed by Ep/Ap ratio (both P < .001) were the best determinants for the discrimination of PSN from normal filling pattern. Ep/Ap ratio, this novel echo-index, increases the diagnostic accuracy of color M-mode Doppler in discriminating normal from PSN filling pattern in patients with left ventricular systolic dysfunction.
Authors:
Alexander P Patrianakos; Frangiskos I Parthenakis; Hercules E Mavrakis; Evangelos A Zacharis; Panos E Vardas
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Publication Detail:
Type:  Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  18     ISSN:  1097-6795     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-12     Completed Date:  2006-04-11     Revised Date:  2007-11-02    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  979     Citation Subset:  IM    
Affiliation:
Cardiology Department, Heraklion University Hospital, Crete, Greece.
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MeSH Terms
Descriptor/Qualifier:
Cardiomyopathy, Dilated / complications,  ultrasonography*
Diastole
Echocardiography, Doppler, Color / methods*
Female
Humans
Male
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Ventricular Dysfunction, Left / etiology,  ultrasonography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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