Document Detail

Late ipsilateral recurrence of ischemic optic neuropathy in giant cell arteritis.
MedLine Citation:
PMID:  12782923     Owner:  NLM     Status:  MEDLINE    
A patient with arteriosclerosis, diabetes mellitus, and giant cell arteritis (GCA) treated continuously with low-dose prednisone developed anterior ischemic optic neuropathy (AION) at 5 and 13 months after clinical diagnosis of GCA. At the time of late recurrent AION, there were no systemic symptoms or elevations in acute phase reactants to signal active arteritis, yet temporal artery biopsy disclosed dramatic inflammation, forcing the presumption that the infarct was arteritic. Recurrent systemic symptoms and elevation of acute phase reactants are not reliable warning signs of reactivated GCA. In patients at high risk for corticosteroid complications, late biopsy may be a reasonable guide to corticosteroid weaning.
Nancy Kim; Jonathan D Trobe; Andrew Flint; Gary Keoleian
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society     Volume:  23     ISSN:  1070-8022     ISO Abbreviation:  J Neuroophthalmol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-03     Completed Date:  2003-07-29     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9431308     Medline TA:  J Neuroophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  122-6     Citation Subset:  IM    
Departments of Ophthalmology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
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MeSH Terms
Aged, 80 and over
Anti-Inflammatory Agents / administration & dosage
Drug Administration Schedule
Fundus Oculi
Giant Cell Arteritis / complications*,  drug therapy,  pathology
Optic Neuropathy, Ischemic / etiology*,  pathology,  physiopathology,  prevention & control
Prednisone / administration & dosage
Recurrence / prevention & control
Temporal Arteries / pathology
Treatment Failure
Visual Acuity
Visual Fields
Reg. No./Substance:
0/Anti-Inflammatory Agents; 53-03-2/Prednisone
Comment In:
J Neuroophthalmol. 2003 Jun;23(2):113-6   [PMID:  12782921 ]

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