Document Detail

Late intramedullary spinal cord metastasis in a patient with lymphoblastic lymphoma: case report.
MedLine Citation:
PMID:  10833629     Owner:  NLM     Status:  MEDLINE    
Late intramedullary spinal cord metastasis of lymphoblastic lymphoma (LBL) is unreported in the literature. The central nervous system (CNS) sites of metastasis previously documented include the spinal leptomeninges causing epidural spinal cord compression or brain praenchymal sites within a year of primary diagnosis. This report represents the first case of intramedullary spinal cord LBL as a late recurrence. The method consists of a case study of one patient with retrospective analysis of tumour tissues from biopsies at ages 5, 9 and 26. The results show that late spinal cord recurrence was microneurosurgically subtotally debulked and later treated with radiotherapy with improvement in neurological deficit. Investigations revealed no evidence of systemic disease and this recurrence appears to be an isolated sanctuary site tumour. A MEDLINE search (1966 - present) of the literature failed to reveal similar reported cases and the authors believe this to be the first late intramedullary spinal cord metastasis in a patient with LBL.
S Mathur; A J Law; N Hung
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  7     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-08-15     Completed Date:  2000-08-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  264-8     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Harcourt Publishers Ltd.
Department of Neurosurgery, Dunedin Hospital, 201 Great King Street, Dunedin, New Zealand.
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MeSH Terms
Child, Preschool
Magnetic Resonance Imaging
Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*
Spinal Cord Neoplasms / radiotherapy,  secondary*,  surgery
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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