| Late hemorrhagic disease of newborn. | |
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MedLine Citation:
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PMID: 12657755 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The clinical features of 14 infants diagnosed with late hemorrhagic disease of newborn (LHDN), of which 10 did not receive vitamin K prophylaxis, are presented. All infants were exclusively breast-fed and 12 did not have any underlying illness to explain the abnormal coagulation profile. The common presenting symptoms were seizures (71%), vomiting (57%), poor feeding (50%) and altered sensorium (36%). Physical examination shared pallor in all infants and a bulging anterior fontanel in 64%. Intracranial bleed was the predominant manifestation (93%), with CT scan showing intracranial bleed in 78%. Eight infants (57%) succumbed to their illness, while 36%had neurological sequelae. Since LHDN leads to significant morbidity and mortality, it should be prevented by providing vitamin K prophylaxis to all newborns. |
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Authors:
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I E D'Souza; S D Subba Rao |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Indian pediatrics Volume: 40 ISSN: 0019-6061 ISO Abbreviation: Indian Pediatr Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-03-26 Completed Date: 2003-05-07 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 2985062R Medline TA: Indian Pediatr Country: India |
Other Details:
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Languages: eng Pagination: 226-9 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, St. John's Medical College Hospital, Bangalore, Karnataka, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Humans Infant, Newborn Male Time Factors Vitamin K Deficiency Bleeding / diagnosis*, prevention & control, therapy* |
| Comments/Corrections | |
Comment In:
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Indian Pediatr. 2003 Aug;40(8):793-4; author reply 794-5
[PMID:
12951387
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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