Document Detail

Late germinal matrix hemorrhage-like lesions in very preterm infants.
MedLine Citation:
PMID:  20595696     Owner:  NLM     Status:  MEDLINE    
In preterm infants, the germinal matrix is a common origin of hemorrhages during the first 7 days of life. Sonographically, germinal matrix hemorrhages present as subventricular echodensities evolving into pseudocysts. Similar lesions have been reported as incidental findings also beyond 7 days of life. They may result from vasculitis and ischemic infarction, rather than hemorrhage. To assess the occurrence, time course, and significance for neurodevelopment of such late germinal matrix hemorrhage-like lesions, we reviewed serial cerebral ultrasound examinations obtained in 86 sequentially admitted infants (gestational age <32 weeks or birth weight <1500 g). Neurodevelopment was assessed at 3 years (Bayley Scales of Infant Development). Nine infants had late isolated germinal matrix hemorrhage-like lesions. Their Psychomotor Development Index scores were significantly lower than that in infants without hemorrhage. Our results suggest that late isolated germinal matrix hemorrhage-like lesions are of clinical significance because of their notable incidence and association with neurodevelopmental outcome.
Sandra Horsch; Patrizia Kutz; Claudia Roll
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  25     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-02     Completed Date:  2010-10-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  809-14     Citation Subset:  IM    
Department of Neonatology, Erasmus Medical Center/Sophia Children's Hospital, Rotterdam, Netherlands.
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MeSH Terms
Child, Preschool
Developmental Disabilities / pathology*,  radiography
Follow-Up Studies
Infant, Newborn
Infant, Premature*
Infant, Very Low Birth Weight*
Intracranial Hemorrhages / pathology*,  radiography
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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