| Late dissemination of pulmonary blastomycosis during ketoconazole therapy. | |
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MedLine Citation:
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PMID: 2909344 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report a patient with pulmonary blastomycosis who suffered relapse with dissemination of her disease after five months of apparent response to therapy with ketoconazole, 400 mg daily. Common causes of drug failure, including noncompliance and failure of absorption, were excluded, and there was no evidence of altered host immunity. Previous reports of relapse during and after ketoconazole therapy are reviewed; no previous case was found with recurrence near the end of a six-month period of apparently effective therapy. Close followup during the entire course of ketoconazole therapy for blastomycosis and following its completion is recommended. |
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Authors:
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C A Hebert; J W King; R B George |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Chest Volume: 95 ISSN: 0012-3692 ISO Abbreviation: Chest Publication Date: 1989 Jan |
Date Detail:
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Created Date: 1989-02-01 Completed Date: 1989-02-01 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0231335 Medline TA: Chest Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 240-2 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, Louisiana State University School of Medicine, Shreveport. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blastomycosis / drug therapy*, pathology, radiography Dermatomycoses / pathology Female Humans Ketoconazole / therapeutic use* Lung / radiography Lung Diseases, Fungal / drug therapy*, radiography Recurrence Skin / pathology |
| Chemical | |
Reg. No./Substance:
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65277-42-1/Ketoconazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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