Document Detail

Late detection of neuroblastoma in a patient with prolonged cerebellar ataxia without opsoclonus.
MedLine Citation:
PMID:  11414640     Owner:  NLM     Status:  MEDLINE    
A 19-month-old boy presented with acute-onset cerebellar ataxia following immunisation. Ataxia was prolonged with a fluctuating course over a period of two years. Opsoclonus was never observed. Extensive diagnostic studies were negative during this time. Finally, a neuroblastoma was discovered. Ataxia disappeared completely during polychemotherapy. This report suggests that occult neuroblastoma must be considered in any child with unexplained prolonged cerebellar ataxia. Specific investigations are recommended for such cases.
M Wolff; M Schöning; G Niemann; I Krägeloh-Mann
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neuropediatrics     Volume:  32     ISSN:  0174-304X     ISO Abbreviation:  Neuropediatrics     Publication Date:  2001 Apr 
Date Detail:
Created Date:  2001-06-20     Completed Date:  2001-12-04     Revised Date:  2008-01-16    
Medline Journal Info:
Nlm Unique ID:  8101187     Medline TA:  Neuropediatrics     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  101-3     Citation Subset:  IM    
Department of Child Neurology, University Children's Hospital, Tübingen, Germany.
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MeSH Terms
Adrenal Gland Neoplasms / diagnosis*,  drug therapy,  surgery
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Cerebellar Ataxia / diagnosis,  drug therapy,  etiology*
Child, Preschool
Combined Modality Therapy
Follow-Up Studies
Neoadjuvant Therapy
Neuroblastoma / diagnosis*,  drug therapy,  surgery
Ocular Motility Disorders / diagnosis,  drug therapy,  etiology*
Paraneoplastic Syndromes / diagnosis,  drug therapy,  etiology*

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