| Late crust formation as a predictor of healing of traumatic, dry, and minor-sized tympanic membrane perforations. | |
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MedLine Citation:
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PMID: 23313119 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: The goal of this study was to evaluate the effects of crust formation on the healing of traumatic, dry, and minor-sized tympanic membrane perforations (TMPs) in humans. STUDY DESIGN: Case series with a chart review. SETTING: Tertiary university hospital. MATERIALS AND METHODS: The clinical records of patients with traumatic TMPs who met the case selection criteria were retrieved and categorized according to the presence of a crust and the timing of crust formation into three groups: no crust, early crust formation, and late crust formation. Healing outcomes (i.e., healing rate and time) in the three groups were analyzed. RESULTS: In total, 83 patients were analyzed. The perforation closure rates were 92%, 100%, and 78% in the groups with no-crust, early crust formation, and late crust formation, respectively. No significant difference was seen between the groups with no-crust and with late crust formation (p>0.05). By contrast, closure rates differed significantly between the early and late crust formation groups (p<0.05). Overall, the no-crust and early crust formation groups showed shorter healing times compared with the late crust formation group (p<0.05). However, closure times did not differ significantly between groups with early crust formation and no crust (p>0.05). CONCLUSIONS: Crust formation at the margin of a traumatic TMP may serve as a predictor of healing outcome. Compared with perforations with early crust formation or no crust, late crust formation can result in delayed healing and failure to close completely. |
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Authors:
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Zhengcai Lou |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-10 |
Journal Detail:
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Title: American journal of otolaryngology Volume: - ISSN: 1532-818X ISO Abbreviation: Am J Otolaryngol Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8000029 Medline TA: Am J Otolaryngol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Otorhinolaryngology, The Affiliated YiWu Hospital of Wenzhou Medical College, Zhejiang, China. Electronic address: louzhengcai@163.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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