| Late Preterm Infants Have Worse 24-Month Neurodevelopmental Outcomes Than Term Infants. | |
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MedLine Citation:
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PMID: 21321024 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Background: Late preterm infants (34-37 weeks' gestation) are often perceived at similar risks for morbidity and mortality as term infants. Objective: To compare the neurodevelopmental outcomes of late preterm to term infants. Methods: Our study sample of 6300 term and 1200 late preterm infants came from the Early Childhood Longitudinal Study-Birth Cohort. We used general estimating equations to get weighted odds of having developmental delay, mental index scores (MDI) or psychomotor index scores (PDI) < 70, at 24 months of age. Results: Late preterm infants compared with term infants had lower MDI (85 vs 89) and PDI (88 vs 92), both P < .0001, respectively. A higher proportion of late preterm infants compared with term infants had an MDI <70 (21% vs 16%; P < .0001). An equal number had PDIs <70 (6.1% vs 6.5%). After controlling for statistically significant and clinically relevant descriptive characteristics, late preterm infants still had higher odds of mental (odds ratio: 1.52 [95% confidence interval: 1.26-1.82] P < .0001) or physical (odds ratio: 1.56 [95% confidence interval: 1.30-1.89] P < .0001) developmental delay. Conclusions: Late preterm infants have poorer neurodevelopmental outcomes than term infants and have increased odds to have a mental and/or physical developmental delay. |
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Authors:
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Melissa A Woythaler; Marie C McCormick; Vincent C Smith |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-2-14 |
Journal Detail:
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Title: Pediatrics Volume: - ISSN: 1098-4275 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-2-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Neonatology, Massachusetts General Hospital, Boston, Massachusetts; |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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