Document Detail

Late echocardiographic and clinical outcomes after mitral valve repair for degenerative disease.
MedLine Citation:
PMID:  19732218     Owner:  NLM     Status:  In-Process    
BACKGROUND AND AIM OF THE STUDY: Mitral valve repair is the procedure of choice for severe degenerative mitral regurgitation (MR). The objective of this study was to review prospectively gathered echocardiographic and clinical results with mitral valve repair for degenerative disease.
METHODS: Between May 1995 and July 2004, 403 patients underwent mitral valve repair for degenerative disease (mean age 63 +/- 12 years, 72% males). Concomitant procedures included CABG (29%), radiofrequency left-sided maze procedure (8%), aortic valve replacement (6%), and tricuspid valve repair (4%).
RESULTS: Thirty-day mortality was 0.4% for patients with isolated mitral valve repair and 5.1% for patients with mitral valve repair and concomitant procedure (p = 0.003). Five-year survival was higher for isolated mitral valve repair compared to mitral valve repair with a combined procedure (92 +/- 2% vs. 76 +/- 5%; p < 0.001). Pulmonary artery pressure and left atrial and left ventricular end-diastolic diameters were significantly improved following mitral valve repair (all p <or= 0.005) and this was sustained afterward. The freedom from severe (3+ or 4+) and moderate-severe (2+, 3+, or 4+) MR was 95% and 77% at 5 years, respectively, whereas the freedom from reoperation was 96 +/- 1% at 5 years. Significant predictors of moderate-severe MR recurrence were cardiac dilatation, anterior leaflet prolapse, and concomitant procedure, whereas mitral valve disease amenable to posterior leaflet resection had a lower risk of MR recurrence.
CONCLUSIONS: Excellent clinical outcomes can be obtained using standard techniques of mitral valve repair of the degenerative valve. MR recurrence is low but nonnegligible, emphasizing the necessity for long-term postoperative echocardiographic follow-up in these patients.
Louis-Mathieu Stevens; Arsène-Joseph Basmadjian; Denis Bouchard; Ismaïl El-Hamamsy; Philippe Demers; Michel Carrier; Louis P Perrault; Raymond Cartier; Michel Pellerin
Related Documents :
8582698 - Diagnostic value of transesophageal compared with transthoracic echocardiography in sus...
18640318 - Left thoracotomy for multiple-time redo mitral valve surgery using on-pump beating hear...
20876188 - Incremental value of three-dimensional transoesophageal echocardiography for guiding do...
12538278 - Combined valve operations with transection of ascending aorta.
16624718 - Ultrasonography of the spleen in 50 healthy cows.
1000628 - Anomalous origin of the right coronary artery from the left sinus of valsalva with asso...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-09-02
Journal Detail:
Title:  Journal of cardiac surgery     Volume:  25     ISSN:  1540-8191     ISO Abbreviation:  J Card Surg     Publication Date:    2010 Jan-Feb
Date Detail:
Created Date:  2010-01-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908809     Medline TA:  J Card Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9-15     Citation Subset:  IM    
Department of Surgery, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Grant Support
//Canadian Institutes of Health Research

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Utilization of the Edge-to-Edge Valve Plasty Technique to Correct Severe Tricuspid Regurgitation in ...
Next Document:  Coronary cameral fistula: left anterior descending artery to left ventricle.