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Late Clinical Outcome after Intracoronary Palmaz-Schatz Stenting with High Pressure Balloon Dilation without Anticoagulation.
MedLine Citation:
PMID:  10762944     Owner:  NLM     Status:  Publisher    
In recent studies, the technique of high pressure balloon dilation for stent optimization has been shown to improve procedural success and to reduce subacute closure after stenting. The late clinical outcome, however, is still uncertain after stenting with high pressure balloon dilation. Therefore, we evaluated the effect of high pressure balloon dilation on the subsequent clinical course in patients after intracoronary stenting. One-hundred ninety patients with 197 lesions were treated with Palmaz-Schatz stent implantation. Intracoronary stenting without high pressure balloon dilation and with anticoagulation was performed in 55 patients with 55 lesions (phase 1), whereas intracoronary stenting with high pressure balloon dilation, without anticoagulation was done in 135 patients with 142 lesions (phase 2). We compared the angiographic and clinical results immediately and at follow-up in both phase 1 and phase 2. Coronary angiography was repeated at 6 months in 147 patients (79%) and 150 lesions (77%). The overall incidence of angiographic restenosis was 24% (31% in phase 1 and 21% in phase 2). Angiographic restenosis occurred in 18% of elective stenting on de novo lesions (23% in phase 1 and 15% in phase 2). The target lesion revascularization rate was 19% (26% in phase 1 and 16% in phase 2). The restenosis rate was significantly reduced with high pressure balloon dilation in the infarct-related artery and for a stent size of ³ 4.0 mm (p < 0.05). In conclusion, intracoronary stenting using high pressure balloon dilation technique without anticoagulation has good immediate results, negligible stent thrombosis and may have a tendency towards lower rates of restenosis.
Park; Park; Hong; Kim; Cheong; Lee; Kang; Song; Choi; Kim
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Publication Detail:
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  9     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  1997 Sep 
Date Detail:
Created Date:  2000-04-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  469-474     Citation Subset:  -    
Departments of Internal Medicine, University of Ulsan, College of Medicine, Cardiovascular Center, Asan Medical Center, 388Ð1 Pungnap-dong, Songpagu, Seoul, Korea.
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