Document Detail


Latanoprost in hemifacial spasm.
MedLine Citation:
PMID:  11789895     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An empirical observation that the prostaglandin derivate latanoprost quited facial spasms in patients with glaucoma prompted us to study latanoprost in non-glaucomatous patients with hemifacial spasms [HFS]. This explorative trial followed an open-label, prospective treatment design. At short term, most patients showed no or only mild improvement and subsequently needed therapy with Botulinum toxin A. Although these results are not impressive, latanoprost could be considered as an interesting alternative in the treatment of patients with HFS and with concomitant glaucoma. A role for prostaglandins in the trigeminofacial reflex is hypothesised.
Authors:
Luc Crevits; Maarten Goethals; Niels Libbrecht; Koen Paemeleire
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Prostaglandins & other lipid mediators     Volume:  67     ISSN:  1098-8823     ISO Abbreviation:  Prostaglandins Other Lipid Mediat.     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-01-14     Completed Date:  2002-08-06     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9808648     Medline TA:  Prostaglandins Other Lipid Mediat     Country:  United States    
Other Details:
Languages:  eng     Pagination:  27-30     Citation Subset:  IM    
Affiliation:
Department of Neurology, Neuro-Ophthalmology Unit, Ghent University Hospital, Belgium. Luc.crevits@rug.ac.be
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MeSH Terms
Descriptor/Qualifier:
Aged
Female
Glaucoma / complications,  drug therapy
Hemifacial Spasm / drug therapy*
Humans
Male
Middle Aged
Prospective Studies
Prostaglandins F, Synthetic / therapeutic use*
Treatment Outcome
Chemical
Reg. No./Substance:
0/Prostaglandins F, Synthetic; 130209-82-4/latanoprost

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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