Document Detail

Laser-induced thermotherapy (LITT) for malignant liver tumours: the role of sonography in catheter placement and observation of the therapeutic procedure
MedLine Citation:
PMID:  12168138     Owner:  NLM     Status:  MEDLINE    
AIM: Evaluation of sonography in the placement of catheters for laser-induced thermotherapy (LITT) as well as for the observation of the therapeutic procedure in cases of malignant liver tumours. METHODS: Following the placement of 1-4 LITT applicators, 18 patients with malignant liver tumours (recurrence of hepatocellular carcinoma n = 5, metachronous liver metastases n = 13) were examined by ultrasound to determine the position of the applicators as well as the sonographic visualisation of the respective lesion. The laser treatment procedure was also observed sonographically. As standard reference method for the documentation of thermally induced necroses we used magnetic resonance tomography 24-48 hours after the procedure. RESULTS: The tip of the applicator could be localised in all cases, and the position of the applicator relative to the lesion could be directly visualised in 78% of cases. The hyperechogenic thermal effect during LITT had a median size of 4.5 cm, thus proving to be significantly larger than the actual necrosis induced (p < 0.01). The sonographic observation of the procedure identified 8/10 primarily incomplete ablations which were then treated again immediately after correction of the position of the applicators. CONCLUSION: Continuous sonographic observation of the procedure of LITT can yield important additional information.
C Stroszczynski; S Gretschel; G Gaffke; R Puls; A Kretzschmar; N Hosten; P M Schlag; R Felix
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Ultraschall in der Medizin (Stuttgart, Germany : 1980)     Volume:  23     ISSN:  0172-4614     ISO Abbreviation:  Ultraschall Med     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-08-08     Completed Date:  2002-10-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8303585     Medline TA:  Ultraschall Med     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  163-7     Citation Subset:  IM    
Diagnostische und Interventionelle Radiologie der Robert-Rössle Klinik, Charité Campus Buch Medizinische Fakultät der Humboldt Universität zu Berlin.
Vernacular Title:
Laser-induzierte Thermotherapie (LITT) bei malignen Lebertumoren: Einsatz der Sonographie zur Katheterplatzierung und Prozessbeobachtung.
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MeSH Terms
Aged, 80 and over
Colorectal Neoplasms / therapy
Hyperthermia, Induced* / methods
Laser Coagulation* / methods
Liver Neoplasms / pathology,  secondary*,  therapy*,  ultrasonography
Middle Aged
Regression Analysis

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