Document Detail

Laser capture microscopy.
MedLine Citation:
PMID:  10889904     Owner:  NLM     Status:  MEDLINE    
Human tissues are composed of complex admixtures of different cell types and their biologically meaningful analysis necessitates the procurement of pure samples of the cells of interest. Many approaches have been used in attempts to overcome this difficulty, including a variety of microdissection methods. This review concerns a recent advance in microdissection techniques, namely laser capture microdissection (LCM). The principle underlying this technique is outlined, and practical issues pertaining to LCM are considered. In addition, the literature relating to LCM is reviewed, with examples of research applications of this technique being outlined.
S Curran; J A McKay; H L McLeod; G I Murray
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Molecular pathology : MP     Volume:  53     ISSN:  1366-8714     ISO Abbreviation:  MP, Mol. Pathol.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-07-19     Completed Date:  2000-07-19     Revised Date:  2013-06-11    
Medline Journal Info:
Nlm Unique ID:  9706282     Medline TA:  Mol Pathol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  64-8     Citation Subset:  IM    
Department of Pathology, University of Aberdeen, Foresterhill, UK.
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MeSH Terms
Cell Separation
Cost-Benefit Analysis
Dissection / economics,  methods*
Microscopy, Confocal / economics,  methods*
Neoplasms / ultrastructure
Specimen Handling / methods

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