Document Detail

Laser-assisted uvulopalatoplasty for obstructive sleep apnea.
MedLine Citation:
PMID:  8544614     Owner:  NLM     Status:  MEDLINE    
Laser-assisted uvulopalatoplasty (LAUP) can reduce snoring by sequentially removing excessive vibratory tissue of the velopharynx. The procedure can be performed under local anesthesia in an office setting. Since the appearance of the soft palate is similar after both LAUP and uvulopalatopharyngoplasty, LAUP may also be efficacious in the management of obstructive sleep apnea syndrome (OSAS). LAUP was performed in 34 consecutive prospectively evaluated patients with OSAS. Of the 34 patients, 28 (82%) were male; the mean age was 53 years, and the mean body mass index was 31.1. In the study population of 13 patients who completed preoperative and postoperative sleep studies, the apnea index decreased from 19.4 to 4.2 (P = .006), the respiratory disturbance index (RDI) decreased from 31.2 to 15.7 (P = .092), and mean lowest oxyhemoglobin saturation increased from 82.3% to 85.0% (P = .581). The RDI fell to 10 or lower in 38.5% of patients and was reduced by at least 50% in 53.8% of the study group. Snoring was significantly reduced in 92.3% of patients (P < .001). These early results suggest that LAUP may be efficacious in the management of OSAS.
S A Mickelson
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  The Laryngoscope     Volume:  106     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  1996 Jan 
Date Detail:
Created Date:  1996-02-13     Completed Date:  1996-02-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  10-3     Citation Subset:  IM    
Department of Otolaryngology-Head and Neck Surgery, Henry Ford Hospital, Detroit, MI 48202, USA.
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MeSH Terms
Aged, 80 and over
Laser Therapy / methods*
Middle Aged
Oxyhemoglobins / analysis
Palate, Soft / surgery*
Prospective Studies
Sleep Apnea Syndromes / physiopathology,  surgery*
Uvula / surgery*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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