| Laser-assisted uvulopalatoplasty for obstructive sleep apnea. | |
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MedLine Citation:
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PMID: 8544614 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Laser-assisted uvulopalatoplasty (LAUP) can reduce snoring by sequentially removing excessive vibratory tissue of the velopharynx. The procedure can be performed under local anesthesia in an office setting. Since the appearance of the soft palate is similar after both LAUP and uvulopalatopharyngoplasty, LAUP may also be efficacious in the management of obstructive sleep apnea syndrome (OSAS). LAUP was performed in 34 consecutive prospectively evaluated patients with OSAS. Of the 34 patients, 28 (82%) were male; the mean age was 53 years, and the mean body mass index was 31.1. In the study population of 13 patients who completed preoperative and postoperative sleep studies, the apnea index decreased from 19.4 to 4.2 (P = .006), the respiratory disturbance index (RDI) decreased from 31.2 to 15.7 (P = .092), and mean lowest oxyhemoglobin saturation increased from 82.3% to 85.0% (P = .581). The RDI fell to 10 or lower in 38.5% of patients and was reduced by at least 50% in 53.8% of the study group. Snoring was significantly reduced in 92.3% of patients (P < .001). These early results suggest that LAUP may be efficacious in the management of OSAS. |
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Authors:
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S A Mickelson |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: The Laryngoscope Volume: 106 ISSN: 0023-852X ISO Abbreviation: Laryngoscope Publication Date: 1996 Jan |
Date Detail:
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Created Date: 1996-02-13 Completed Date: 1996-02-13 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8607378 Medline TA: Laryngoscope Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 10-3 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology-Head and Neck Surgery, Henry Ford Hospital, Detroit, MI 48202, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Female Humans Laser Therapy / methods* Male Middle Aged Oxyhemoglobins / analysis Palate, Soft / surgery* Prospective Studies Sleep Apnea Syndromes / physiopathology, surgery* Uvula / surgery* |
| Chemical | |
Reg. No./Substance:
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0/Oxyhemoglobins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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